≪２０２３年≫
Yingyue Q, Sugawara K, Takahashi H, Yokoi N, Ohbayashi K, Iwasaki Y, Seino S, Ogawa W.
Stimulatory effect of imeglimin on incretin secretion.
Journal of Diabetes Investigation 2023 (published online)
≪２０２２年≫
Ohno T, Miyasaka Y, Yoshida K, Kobayashi M, Horio F, Yokoi N, Mizuno M, Ikegami H.
A novel model mouse for type 2 diabetes mellitus with early onset and persistent hyperglycemia.
Experimental Animals 71(4):510-518, 2022
Yoshida M, Yokoi N, Takahashi H, Hatano N, Hayami T, Ogawa W, Seino S.
O-GlcNAcylation of myocyte-specific enhancer factor 2D negatively regulates insulin secretion from pancreatic β-cells.
Biochemical Biophysical Research Communications 605:90-96, 2022
≪２０２１年≫
Murao N, Yokoi N, Takahashi H, Hayami T, Minami Y, Seino S.
Increased glycolysis affects β-cell function and identity in aging and diabetes.
Molecular Metabolism 55:101414, 2021
足立裕哉、平野 亘、谷口幸雄、横井伯英.
肉用牛の肉量および肉質のバイオマーカーとしての血中マイクロRNAの可能性.
肉用牛研究会報 111:7-12, 2021
Han G, Takahashi H, Murao N, Gheni G, Yokoi N, Hamamoto Y, Asahara SI, Seino Y, Kido Y, Seino S.
Glutamate is an essential mediator in glutamine-amplified insulin secretion.
Journal of Diabetes Investigation 12(6):920-930, 2021
≪２０２０年≫
Oduori OS, Murao N, Shimomura K, Takahashi H, Zhang Q, Dou H, Sakai S, Minami K, Chanclon B, Guida C, Kothegala L, Tolo J, Maejima Y, Yokoi N, Minami Y, Miki T, Rorsman P, Seino S.
Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes.
Journal of Clinical Investigation 130(12):6639-6655, 2020
Hayami T, Yokoi N, Yamaguchi T, Honda K, Murao N, Takahashi H, Wang S, Seino Y, Kamiya H, Yabe D, Sweet IR, Mizoguchi A, Nakamura J, Seino S.
Tumor-like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin-induced insulin secretion in obese diabetes: a study of ZFDM rat.
Journal of Diabetes Investigation 11:1434-1447, 2020
Kanno A, Asahara SI, Furubayashi A, Masuda K, Yoshitomi R, Suzuki E, Takai T, Kimura-Koyanagi M, Matsuda T, Bartolome A, Hirota Y, Yokoi N, Inaba Y, Inoue H, Matsumoto M, Inoue K, Abe T, Wei FY, Tomizawa K, Ogawa W, Seino S, Kasuga M, Kido Y.
GCN2 regulates pancreatic β cell mass by sensing intracellular amino acid levels.
JCI Insight 5(9):e128820, 2020
横井伯英.
動物モデルを用いた1型糖尿病の遺伝因子の同定と病態解明.
糖尿病・内分泌代謝科 51(4):266-273, 2020
≪２０１９年≫
Carmean CM, Yokoi N, Takahashi H, Oduori OS, Kang C, Kanagawa A, Kirkley AG, Han G, Landeche M, Hidaka S, Katoh M, Sargis RM, Seino S.
Arsenic modifies serotonin metabolism through glucuronidation in pancreatic β-cells.
American Journal of Physiolgy-Endocrinology and Metabolism 316:E464-E474, 2019
Takahashi H, Yokoi N, Seino S.
Glutamate as intracellular and extracellular signals in pancreatic islet functions.
Proceedings of the Japan Academy, Ser. B 95:1-15, 2019
≪２０１８年≫
Hashim M, Yokoi N, Takahashi H, Gheni G, Okechi OS,Hayami T, Murao N, Hidaka S, Minami K, Mizoguchi A, Seino S.
Inhibition of SNAT5 induces incretin responsive state from incretin unresponsive state in pancreatic β-cells: study of β-cell spheroid clusters as a model.
Diabetes 67:1795-1806, 2018
Okada D, Endo S, Matsuda H, Ogawa S, Taniguchi Y, Katsuta T, Watanabe T, Iwaisaki H.
An intersection network based on combining SNP coassociation and RNA coexpression networks for feed utilization traits in Japanese Black cattle.
J Anim Sci 96(7):2553-2566, 2018
≪２０１７年≫
Murao N, Yokoi N, Hoada K, Han G, Hayami T, Gheni G, Takahashi H, Minami K, Seino S.
Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion.
PLoS One 12:e0187213, 2017
Nakanishi S, Kuramoto T, Kashiwazaki N, Yokoi N.
Genetic profiling of two phenotypically distinct outbred rats derived from a colony of the Zucker fatty rats maintained at the Tokyo Medical University.
Experimental Animals 66:91-98, 2017
Tsuji H, Taniguchi Y, Ishizuka S, Matsuda H, Yamada T, Naito K, Iwaisaki H.
Structure and polymorphisms of the major histocompatibility complex in the Oriental stork, Ciconia boyciana.
Scientific Reports 7:42864, 2017
≪２０１６年≫
Ogawa, S., Matsuda, H., Taniguchi, Y., Watanabe, T., Kitamura, Y., Tabuchi, I., Sugimoto, Y. and Iwaisaki, H.
Genomic prediction for carcass traits in Japanese Black cattle using single nucleotide polymorphism markers of different densities.
Animal Production Science 57, 1631-1636, 2016
Ogawa, S., Matsuda, H., Taniguchi, Y., Watanabe, T., Sugimoto, Y. and Iwaisaki, H.
Estimated genetic variance explained by single nucleotide polymorphisms of different minor allele frequencies for carcass traits in Japanese Black Cattle.
Journal of Biosciences and Medicines 4, 89-97, 2016
Honda, T., Ishida, T., Kobayashi, I., Oguri, Y., Mizuno, Y., Mannen, H., Iwaisaki, H., Kuge, S., Saito, K. and Oyama, K.
Change of fatty acid composition of the lumbar longissimus during the final stage of fattening in the Japanese Black cattle.
Animal Science Journal 87, 578-583, 2016
Link
Wajiki, Y., Kaneko, Y., Sugiyama, T., Yamada, T. and Iwaisaki, H.
Genetic analyses in the Japanese captive population of Japanese crested ibis (Nipponia nippon) using pedigree information.
The Journal of Poultry Science 53, 1-7, 2016
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Ogawa, S., Matsuda, H., Taniguchi, Y., Watanabe, T., Takasuga, A., Sugimoto, Y. and Iwaisaki, H.
Accuracy of imputation of single nucleotide polymorphism marker genotypes from low-density panels in Japanese Black cattle.
Animal Science Journal 87, 3-12, 2016
Link
≪２０１５年≫
Gheni G, Yokoi N, Beppu M, Yamaguchi T, Hidaka S, Kawabata A, Hoshino Y, Hoshino M, Seino S.
Characterization of the prediabetic state in a novel rat model of type 2 diabetes, the ZFDM rat.
Journal of Diabetes Research 2015:261418, 2015
Yokoi N, Beppu M, Yoshida E, Hoshikawa R, Hidaka S, Matubara T, Shinohara M, Irino Y, Hatano N, Seino S.
Identification of putative biomarkers for prediabetes by metabolome analysis fo rat models of type 2 diabetes.
Metabolomics 11:1277-1286, 2015
Yamada, T., Nagata, H., Taniguchi, Y., Matsuda, H., Ohta, T., Sugiyama, T., Homma, K., Kaneko, Y. and Iwaisaki, H.
Molecular assessment of genetic diversity in the Japanese population of the Japanese crested ibis.
Ornithological Science 2015
Ogawa, S., Matsuda, H., Taniguchi, Y., Watanabe, T., Sugimoto, Y. and Iwaisaki, H.
Estimation of variance and genomic prediction using genotypes imputed from low-density marker.
Animal Science Journal 2015 doi: 10.1111/asj.12570.
Link
≪２０１４年≫
Gheni G, Ogura M, Iwasaki M, Yokoi N, Minami K, Nakayama Y, Harada K, Hastoy B, Wu X, Takahashi H, Kimura K, Matsubara T, Hoshikawa R, Hatano N, Sugawara K, Shibasaki T, Inagaki N, Bamba T, Mizoguchi A, Fukusaki E, Rorsman P, Seino S.
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify secretion.
Cell Reports 9:661-673, 2014
Takagi, Y., Matsuda, H., Taniguchi, Y. and Iwaisaki, H.
Predicting the phenotypic values of physiological traits using SNP genotype and gene expression data in mice.
PLoS One 9, e115532, 2014
Link
Taniguchi, Y., Matsumoto, K., Matsuda, H., Yamada, T., Sugiyama, T., Homma, K., Kaneko, Y., Yamagishi, S. and Iwaisaki, H.
Structure and polymorphism of the major histocompatibility complex class II region in the Japanese crested ibis, Nipponia Nippon.
PLoS One 9,e108506, 2014
Link
Yamashita, M., Komatsu, Y., Yamada, T., Tong, B., Ohta, T., Sugiyam,a T., Yamashiro, H., Kaneko, Y., Nagata, H. and Iwaisaki, H.
Polymorphisms of the dopamine receptor D4 gene in the Sado population of the Japanese crested ibis.
The Journal of Animal Genetics 42, 65-69, 2014
Link
Wajiki, Y., Kaneko, Y., Sugiyama, T., Yamada, T. and Iwaisaki, H.
Demographic Analyses in the Japanese Captive Population of Japanese Crested Ibis (Nipponia nippon).
Japanese Journal of Zoo and Wildlife Medicine 19, 57-67, 2014
Link
Komatsu, Y., Yamashita, M., Yamada, T., Tong, B., Ohta, T., Sugiyama, T., Yamashiro, H., Kaneko, Y., Nagata, H. and Iwaisaki H.
The nucleotide sequences for the dopamine receptor D4 gene in the Japanese crested ibis.
The Journal of Animal Genetics 42, 3-9, 2014
Link
入江正和・祝前博明.
牛の未来.
畜産の研究 68, 412-419, 2014
Tsubono, K., Taniguchi, Y., Matsuda, H., Yamada, T., Sugiyama, T., Homma, K., Kaneko, Y., Yamagishi, S. and Iwaisaki, H.
Identification of novel genetic markers and evaluation of genetic structure in a population of Japanese crested ibis.
Animal Science Journal 85, 356-364, 2014
Link
Ogawa, S., Matsuda, H., Taniguchi, Y., Watanabe, T., Nishimura, S., Sugimoto, Y. and Iwaisaki, H.
Effects of single nucleotide polymorphism marker density on degree of genetic variance explained and genomic evaluation for carcass traits in Japanese Black beef cattle.
BMC Genetics 15, 15, 2014
Link
Watanabe,T., Matsuda, H., Arakawa, A., Yamada, T., Iwaisaki, H., Nishimura, S. and Sugimoto, Y.
Estimation of variance components for carcass traits in Japanese Black cattle using 50K SNP genotype data.
Animal Science Journal 85, 1-7, 2014
Link
≪２０１３年≫
Yokoi N, Hoshino M, Hidaka S, Yoshida E, Beppu M, Hoshikawa R, Sudo K, Kawada A, Takagi S, Seino S.
A novel rat model of type 2 diabetes: the Zucker Fatty Diabetes Mellitus ZFDM rat.
Journal of Diabetes Research 2013:103731, 2013
